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Clash of options leaves Deutsche Telekom struggling FT.com
... similar saga after a study questioned the cardiac side effects of GlaxoSmithKline's diabetes drug Avandia two years ago, which cut sales sharply. But in writing ahead of the media, ...

5 myths about America's ailing health-care system News-Journal
... want to improve care. Tracking the rate of heart attacks from drugs such as Avandia is key to ensuring safe pharmaceuticals. Let's just say that we could wave a ...

Master Stem Cell for Human Heart Identified Yahoo Italia
... out that many widely used and valuable drugs, such as Herceptin (for cancer) and Avandia (for ), have heart-related side effects. The painkiller Vioxx was withdrawn from the market ...

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UPDATE 2-US FDA questions cancer link with Sanofi's Lantus Reuters
... severe as the 60 percent drop seen in global sales of GlaxoSmithKline's ( ) Avandia, which was linked to heart attack risk in 2007, he said. The FDA posted ...

Alogliptin delayed; cancer concerns with insulin glargine theheart.org
... about the cardiovascular safety of drugs in this field, especially the thiazolidinediones, including rosiglitazone (Avandia, GlaxoSmithKline). Takeda was informed in March that the available safety data were insufficient for ...



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Avandia (Rosiglitazone)


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  Avandia

Common uses

This medicine is used to treat type 2 diabetes by reducing the resistance your body has to insulin. It is used either alone or in combination with other anti-diabetes medicines, including metformin or insulin, as part of a diet and exercise program.

Before using

Additional monitoring of your dose or condition may be needed if you are taking other medicine for diabetes. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding. Use of Avandia is not recommended if you have newly diagnosed or worsening heart failure (acute congestive heart failure) or type 1 diabetes. Additional monitoring of your dose or condition may be needed if you have heart disease (e.g., chronic congestive heart failure) or liver disease. Contact your doctor or pharmacist if you have any questions or concerns about taking Avandia.

Directions

Follow the directions for using Avandia provided by your doctor. This medicine may be taken on an empty stomach or with food. Store Avandia at room temperature at 77 degrees f (25 degrees c) in a tightly-closed container, away from heat, moisture, and light. If you miss a dose of Avandia, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Cautions

Do not stop using Avandia or other diabetes medicine without first checking with your doctor. Check with your doctor before adjusting the dose of your diabetes medicine or changing your diet. Keep all doctor and laboratory appointments (e.g., liver function test) while you are using Avandia. Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist.

For women: Avandia may increase your chance of pregnancy by causing ovulation to resume in women who have not been ovulating. Consult your doctor or pharmacist about the use of reliable birth control while using Avandia. If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy. It is unknown if Avandia is excreted in breast milk. Do not breast-feed while taking Avandia.

Possible side effects

No common side effects have been reported with the proper use of Avandia. Check with your doctor as soon as possible if you experience unusual tiredness or weakness. Contact your doctor immediately if you experience the following side effects: nausea; vomiting; stomach pain; fatigue; loss of appetite; unusual thirst; unusual amount of urine; dark urine; rapid weight gain; bloating or swelling of ankles, feet, or hands; chest pain; or shortness of breath. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

If you take too much

If overdose is suspected, contact your local poison control center or emergency room immediately.

Additional information

Follow the dietary plan provided by your doctor. Carry an identification card at all times that says you are diabetic. Monitor your blood sugar levels regularly according to your doctor's directions. If your blood sugar level is often higher than it should be and you are taking Avandia according to directions, check with your doctor.

Do not share Avandia with others for whom it was not prescribed. Do not use Avandia for other health conditions. Keep this product out of the reach of children. If using Avandia for an extended period of time, obtain refills before your supply runs out.

Drug interactions

Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Some medicines or medical conditions may interact with Avandia. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking.

 
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